Agilent Genomics Webinar Series Ask the Experts

Magnis – Your automated research partner
Date: záznam k dispozici ZDE
Speaker: Brigette Brown-Kipphut, Agilent Technologies

Next Generation Sequencing technology allows molecular pathologists to profile samples for various generic aberrations. Many challenges exist with bringing technologies and methods to a laboratory, including the expertise required to develop, optimize, and validate assays protocols for use in diverse applications. The Agilent Magnis NGS Prep system was designed to run complex NGS library assay with minimal technical knowledge and hands-on time – all with the press of a button. This webinar will explore the Magnis instrument along with running its NGS protocol.

Exomes today and tomorrow
Date: November 30, 2021
Time: 11:00 CET
Speaker: Kathleen Corcoran & Jennifer Jones, Agilent Technologies
Záznam k dispozici ZDE

As the goals and needs of scientist evolve regarding next generation sequencing, the role of performing exon enrichment has also evolved. Utility and application of Exomes are impacted by both content as well as overall structure and sample options.This presentation will discuss the type of applications and content utilized today with Exome sequencing and the promise of relevance in the future.

Demystifying molecular barcodes (UMIs) for RNA-Seq experiments
Date: December 14, 2021
Time: 11:00 CET
Speaker: Jean Jasinski, Agilent Technologies
Registrace ZDE

Agilent introduced a library prep for RNA sequencing that includes dual molecular barcodes ( or universal molecular identifiers).This presentation will discuss when and how the MBCs should be used in RNA-Seq data analysis.

Improving resolution through Capture HiC
Date: January 11, 2022
Time: 11:00 CET
Speaker: Justin Lenhart, Agilent Technologies
Registrace ZDE

High throughput chromatin conformation capture (HiC) provides a means to generate genome-wide chromatin architecture maps.

Despite this utility, HiC is a genome-wide sequencing assay that can be limited due to relatively high costs while simultaneously failing to attain high-enough resolution to identify individual chromatin loops. To address these problems, Agilent has partnered with Arima Genomics to generate a streamlined target enrichment workflow for HiC (capture HiC).

During this webinar, this streamlined capture HiC workflow will be presented, highlighting how it allows researchers to focus HiC reads on targeted areas of the genome, reducing sequencing read requirements (and, hence, cost) for high-resolution HiC workflows.

New GenetiSure Cyto CGH : An improved design focused on what matters
Date: January 25, 2022
Time: 11:00 CET
Speaker: Doug Blake, Agilent Technologies
Registrace ZDE

aCGH technology has become a staple in genetic laboratories. The platform, however, is only as good as the design of the array. Agilent has released the most up-to-date platform design in the Agilent GenetiSure Cyto CGH arrays.

Clinically relevant targets have been updated to incorporate current literature recommendations and a higher resolution in these target regions.

In this presentation, we will review a recent experience of a clinical laboratory that validated these designs for clinical LDT use. We will compare the designs to the older design and review the overall performance characteristics of the new designs.